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Lymphoma Pathology


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Hodgkin disease results in enlargement of the lymph nodes and spleen. Whereas Hodgkin disease generally has a high cure rate, non-Hodgkin lymphomas are often more difficult to treat. Burkitt lymphoma is a non-Hodgkin type. 

It is known that CD3 and CD20 are homogenously expressed in T lineage and B lineage lymphoma, respectively. CD20 and CD3 are commonly used as specific markers of B and T lineage lymphomas, respectively.

Celnovte CD3(C3E7)-Lymphoma-200×

Celnovte CD20(C4A11)-Lymphoma-200×

Pathological examination is the main means of diagnosis of lymphoma. The pathological diagnosis of lymphoma requires comprehensive application of morphology, immunohistochemistry, genetics and molecular biology techniques, and flow cytometry, etc.

  • Morphology: It is very important in the pathological diagnosis of lymphoma. Different types of lymphoma have characteristic and diagnostic morphological features.
  • IHC: It can be used to identify immunophenotype of lymphoma cells, such as B or T/NK cells, tumor cell differentiation and maturity, etc. By combining with related IHC markers, differential diagnosis of different pathological subtypes can be performed.

Celnovte CD5(C6A10)-Lymphoma-200×

Celnovte CD10(C6D1)-Lymphoma-200×

Celnovte TDT(C2C8)-Lymphoma-200×

More deteils https://www.celnovte-bio-tech.com/product-center/?cat=5

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  • FISH (fluorescence in situ hybridization) detection technology:It can find specific chromosomal breaks, translocations, amplifications, etc., which have guiding significance for the auxiliary diagnosis of specific chromosomal abnormalities related lymphomas, such as Burkitt lymphoma t(8;14) translocations, follicular lymphoma t(14;18) translocation, etc.

More details https://www.celnovte-bio-tech.com/product-center/?cat=10

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